Iron-acquisition Ability of Edwardsiella tarda with Involvement in Its Virulence.
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چکیده
منابع مشابه
Role of type III secretion in Edwardsiella tarda virulence.
Edwardsiella tarda is a Gram-negative enteric bacterium affecting both animals and humans. Recently, a type III secretion system (TTSS) was found in Ed. tarda. Such systems are generally used by bacterial pathogens to deliver virulence factors into host cells to subvert normal cell functions. Genome-walking was performed from the eseB and esrB genes (homologues of Salmonella sseB and ssrB, resp...
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UNLABELLED Edwardsiella tarda is an important pathogenic bacterium that can replicate in macrophages. However, how the intramacrophage infection process affects the virulence of this bacterium is essentially unknown. Here, we show that E. tarda replicates and induces a caspase-1-dependent cell pyroptosis in a murine macrophage model. Via pyroptosis, intracellular E. tarda escapes to the extrace...
متن کاملExpression of an iron-regulated hemolysin by Edwardsiella tarda.
The ability of Edwardsiella tarda to hemolyse red blood cells was investigated. Most E. tarda strains (> 80%) produced a hemolysin when assayed by either an agar overlay or contact-dependent hemolysis technique. This activity was cell-associated (CAH) and not released into the culture supernatant under routine conditions. When quantified, E. tarda strains significantly produced 30-40-fold highe...
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Edwardsiella tarda (E. tarda) is a rare human pathogen; however, the overall mortality of bacteremia is reported to be up to 50%. Here, we describe a case of cholangitis with E. tarda bacteremia who had a pancreatoduodenectomy for a locally advanced gastric cancer. He was successfully treated using a cefmetazole, a second generation cephalosporin for 14 days. To the best of our knowledge, this ...
متن کاملNatural colistin resistance in Edwardsiella tarda.
All of 37 recent human isolates of Edwardsiella tarda were resistant to colistin. All strains were resistant to 6.3 mug of sodium colistimethate per ml; 82% of them were resistant to 100 mug/ml. With 34 Salmonella strains, the average minimal inhibitory concentration (MIC) was 1.6 mug of sodium colistimethate per ml. There was virtually no overlapping of MIC values between both groups of bacter...
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ژورنال
عنوان ژورنال: Fish Pathology
سال: 2002
ISSN: 0388-788X,1881-7335
DOI: 10.3147/jsfp.37.53